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药物能诱发糖尿病吗?

Can diabetes mellitus be induced by medication?

作者信息

Saito Ema, Kafantaris Vivian

机构信息

Division of Child and Adolescent Psychiatry, Schneider Children's Hospital, North Shore Long Island Jewish Health System, New Hyde Park, New York 11040, USA.

出版信息

J Child Adolesc Psychopharmacol. 2002 Fall;12(3):231-6. doi: 10.1089/104454602760386914.

DOI:10.1089/104454602760386914
PMID:12427296
Abstract

The possible relation between diabetes mellitus and the use of psychotropic medications in adult psychiatric patients has been discussed in the literature. In child and adolescent psychiatry, however, there have been only two previous case reports of an adolescent who developed diabetes mellitus while receiving psychotropic medications. We present three adolescents who developed diabetes mellitus after combined treatment with divalproex sodium and atypical antipsychotics. All were African American, obese, and had a family history of diabetes mellitus. We discuss each case and examine the possibility of psychotropic medication-induced diabetes mellitus in adolescents.

摘要

糖尿病与成年精神病患者使用精神药物之间的可能关系已在文献中进行了讨论。然而,在儿童和青少年精神病学领域,之前仅有两例关于青少年在接受精神药物治疗时患糖尿病的病例报告。我们报告了三名青少年,他们在联合使用丙戊酸钠和非典型抗精神病药物治疗后患上了糖尿病。所有患者均为非裔美国人,肥胖,且有糖尿病家族史。我们讨论了每个病例,并探讨了青少年中精神药物诱发糖尿病的可能性。

相似文献

1
Can diabetes mellitus be induced by medication?药物能诱发糖尿病吗?
J Child Adolesc Psychopharmacol. 2002 Fall;12(3):231-6. doi: 10.1089/104454602760386914.
2
Atypical antipsychotics and diabetes mellitus.非典型抗精神病药物与糖尿病
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Metabolic and cardiovascular adverse events associated with antipsychotic treatment in children and adolescents.儿童和青少年抗精神病药物治疗相关的代谢及心血管不良事件。
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Antipsychotic medication use among children and risk of diabetes mellitus.抗精神病药物在儿童中的使用与糖尿病风险。
Pediatrics. 2011 Dec;128(6):1135-41. doi: 10.1542/peds.2011-0855. Epub 2011 Nov 21.
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Pharmacologic treatment of hospitalized patients with schizoaffective disorder.住院双相情感障碍精神分裂症患者的药物治疗。
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Relationship of atypical antipsychotics with development of diabetes mellitus.非典型抗精神病药物与糖尿病发生的关系。
Ann Pharmacother. 2003 Dec;37(12):1849-57. doi: 10.1345/aph.1D142.
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Report on an open-label prospective study of divalproex sodium for the behavioral and psychological symptoms of dementia as monotherapy and in combination with second-generation antipsychotic medication.丙戊酸镁缓释片用于治疗痴呆的行为和心理症状的开放标签前瞻性研究报告:单药治疗及与第二代抗精神病药物联合治疗
Am J Geriatr Pharmacother. 2007 Sep;5(3):209-17. doi: 10.1016/j.amjopharm.2007.09.001.
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New-onset treatment-dependent diabetes mellitus and hyperlipidemia associated with atypical antipsychotic use in older adults without schizophrenia or bipolar disorder.新型抗精神病药物治疗相关的糖尿病和血脂异常与老年非精神分裂症或双相障碍患者使用非典型抗精神病药物有关。
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引用本文的文献

1
Management of schizophrenia in children and adolescents: focus on pharmacotherapy.儿童和青少年精神分裂症的管理:关注药物治疗。
Drugs. 2011 Jan 22;71(2):179-208. doi: 10.2165/11585350-000000000-00000.
2
Atypical antipsychotic-induced diabetes mellitus in child and adolescent psychiatry.儿童及青少年精神病学中不典型抗精神病药物所致糖尿病
CNS Drugs. 2007;21(12):1035-8. doi: 10.2165/00023210-200721120-00006.
3
Children with schizophrenia: clinical picture and pharmacological treatment.患有精神分裂症的儿童:临床表现与药物治疗。
CNS Drugs. 2006;20(10):841-66. doi: 10.2165/00023210-200620100-00005.
4
Benefit-risk assessment of atypical antipsychotics in the treatment of schizophrenia and comorbid disorders in children and adolescents.非典型抗精神病药物治疗儿童和青少年精神分裂症及共病的获益-风险评估
Drug Saf. 2004;27(14):1135-56. doi: 10.2165/00002018-200427140-00005.