Gumprecht Kamila, Sieroń-Rokicka Bogusława, Gumprecht Janusz, Grzeszczak Władysław
Kliniki Intensywnej Terapii Dzieciecej II Katedry Pediatrii, Slaskiej Akademii Medycznej w Katowicach.
Wiad Lek. 2002;55(7-8):373-81.
The aim of the study was to examine the influence of the respiratory insufficiency in infants treated conservatively or with the use of mechanical lung ventilation, on cardiovascular activity of the autonomic nervous system and interdependence of the sympathic and parasympathic system in infants. The cardiovascular autonomic nervous system functions were estimated by the power spectrum analysis of the heart rate variability (PS/HRV) using MEDEA HRV system. HRV spectrum analysis was limited to low (LF: 0.05-0.2 Hz) and high (HF: 0.2-0.6 Hz) frequency components, which were indicators of the sinoatrial node modulation by sympathic (LF) or parasympathic (HF) nervous system. LF/HF ratio presents the independence of the sympathic and parasympathic nervous system activity, and the total power spectrum of the HRV is the whole vegetative system activity index. The medical research was carried out in 44 infants. They included 29 infants with respiratory insufficiency conservatively treated in intensive care unit and 15 healthy control subjects. All infants with respiratory insufficiency were examined twice: during respiratory insufficiency and after recovery (40-64 days from first examination). Healthy infants were examined only once. According to the HRV parameters analysis it was proved that in infants respiratory insufficiency has significant influence on the increased cardiovascular activity of the parasympathic system, and increased cardiovascular activity of the autonomic nervous system. Respiratory insufficiency significantly changes relationship between cardiovascular activity of the sympathic and parasympathic nervous system. Regression of respiratory insufficiency symptoms causes the normalisation of both sympathic and parasympathic activity.
本研究的目的是探讨保守治疗或使用机械通气治疗的婴儿呼吸功能不全对自主神经系统心血管活动以及婴儿交感和副交感神经系统相互依存关系的影响。使用MEDEA HRV系统通过心率变异性功率谱分析（PS/HRV）评估心血管自主神经系统功能。HRV频谱分析限于低频（LF：0.05 - 0.2 Hz）和高频（HF：0.2 - 0.6 Hz）成分，它们分别是交感神经（LF）或副交感神经（HF）对窦房结调节的指标。LF/HF比值表示交感和副交感神经系统活动的独立性，HRV的总功率谱是整个自主神经系统活动指数。该医学研究对44名婴儿进行。其中包括29名在重症监护病房接受保守治疗的呼吸功能不全婴儿和15名健康对照受试者。所有呼吸功能不全的婴儿均接受两次检查：在呼吸功能不全期间和恢复后（首次检查后40 - 64天）。健康婴儿仅检查一次。根据HRV参数分析证明，婴儿呼吸功能不全对副交感神经系统心血管活动增加以及自主神经系统心血管活动增加有显著影响。呼吸功能不全显著改变交感和副交感神经系统心血管活动之间的关系。呼吸功能不全症状的消退导致交感和副交感活动均恢复正常。
