Nisbet Alan A, Thompson Ian M
Division of Urology, Department of Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.
Urology. 2002 Nov;60(5):775-9. doi: 10.1016/s0090-4295(02)01951-9.
To evaluate, in a population of patients with very high risk of diabetes, the natural history of Fournier's gangrene (FG) and to characterize the differences in presentation and outcome.
Patients with FG were identified during a 6-year period at two tertiary care institutions in San Antonio, Texas. The impact of diabetes on presentation and outcome were evaluated and compared with previous series.
We identified 26 patients with FG, of whom 20 (76.9%) had diabetes. Diabetes was the most common risk factor identified and was associated with a younger age. The average hospital stay was not affected by the diagnosis of diabetes. Of 26 patients treated for FG, 3 (11%) died, 1 of whom had diabetes. Although the extent of debridement required was greater among diabetics, the average number of debridements required was not increased (2.55 in diabetic and 2.4 in nondiabetic patients).
Although diabetes is a risk factor for FG, the outcome is not affected by this diagnosis.
在糖尿病极高风险人群中评估福尼尔坏疽（FG）的自然病程，并描述其临床表现和结局的差异。
在德克萨斯州圣安东尼奥市的两家三级医疗机构中，于6年期间确定患有FG的患者。评估糖尿病对临床表现和结局的影响，并与既往系列研究进行比较。
我们确定了26例FG患者，其中20例（76.9%）患有糖尿病。糖尿病是最常见的危险因素，且与较年轻的年龄相关。糖尿病诊断并未影响平均住院时间。在接受FG治疗的26例患者中，3例（11%）死亡，其中1例患有糖尿病。尽管糖尿病患者所需清创范围更大，但所需清创的平均次数并未增加（糖尿病患者为2.55次，非糖尿病患者为2.4次）。
尽管糖尿病是FG的一个危险因素，但该诊断并不影响结局。
