Hislop Alison A
Unit of Vascular Biology and Pharmacology, Institute of Child Health, London, UK.
J Anat. 2002 Oct;201(4):325-34. doi: 10.1046/j.1469-7580.2002.00097.x.
In the adult lung the pulmonary arteries run alongside the airways and the pulmonary veins show a similar branching pattern to the arteries, though separated from them. During early fetal development the airways act as a template for pulmonary blood vessel development in that the vessels form by vasculogenesis around the branching airways. In later lung development the capillary bed is essential for alveolar formation. This paper reviews evidence for the interaction of the airways and blood vessels in both normal and abnormal lung development.
在成人肺中,肺动脉与气道并行,肺静脉虽与动脉分开,但显示出与动脉相似的分支模式。在胎儿发育早期,气道作为肺血管发育的模板,血管通过血管生成在分支气道周围形成。在肺发育后期,毛细血管床对肺泡形成至关重要。本文综述了在正常和异常肺发育过程中气道与血管相互作用的证据。