den Otter G
Arch Chir Neerl. 1975;27(4):229-35.
In a series of 102 patients with multiple injury including a blunt lesion of the chest treated in 1970 through 1973 the mortality rate could be reduced to 17 per cent. This compares favourably with a mortality of about 34 per cent in a similar group of patients treated in the same hospital during 1965 through 1969. The improvement is partly due to increasing experience of the surgical and anaesthesiological teams and especially to a better appreciation of the importance of ventilatory pulmonary insufficiency and acute respiratory distress syndrome which are frequent in these patients. Early respiratory assistance is indicated in all cases with an instability of the chest wall. The imminence of a respiratory distress syndrome may announce itself by the classical symptoms of an increased breathing rate with hypocarbia before hypoxia becomes manifest. In the majority of patients with a thoracic lesion however the syndrome starts with a combination of increasing dyspnoea and normo- or even hypercarbia. This should be recognized and promptly treated by artificial respiration before acidosis and hypoxia with cardiac arrest can occur.
在1970年至1973年期间治疗的102例多处受伤(包括胸部钝性损伤)患者中,死亡率可降至17%。这与1965年至1969年期间在同一家医院治疗的类似患者组中约34%的死亡率相比更有利。这种改善部分归因于外科和麻醉团队经验的增加,尤其是对这些患者中常见的通气性肺功能不全和急性呼吸窘迫综合征的重要性有了更好的认识。所有胸壁不稳定的病例均需早期呼吸支持。呼吸窘迫综合征的临近可能在缺氧显现之前,通过呼吸频率增加伴低碳酸血症的典型症状表现出来。然而,在大多数胸部损伤患者中,该综合征始于进行性呼吸困难与正常或甚至高碳酸血症的合并出现。在酸中毒和缺氧导致心脏骤停发生之前,应认识到这一点并通过人工呼吸及时治疗。