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一项关于表达性写作对参加转移性肾细胞癌疫苗治疗II期试验患者心理和行为调整影响的初步研究。

A pilot study of the effects of expressive writing on psychological and behavioral adjustment in patients enrolled in a Phase II trial of vaccine therapy for metastatic renal cell carcinoma.

作者信息

de Moor Carl, Sterner Janet, Hall Martica, Warneke Carla, Gilani Zunera, Amato Robert, Cohen Lorenzo

机构信息

Department of Behavioral Science, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.

出版信息

Health Psychol. 2002 Nov;21(6):615-9. doi: 10.1037//0278-6133.21.6.615.

DOI:10.1037//0278-6133.21.6.615
PMID:12433015
Abstract

Forty-two patients with metastatic renal cell carcinoma who were participating in a Phase II clinical trial were randomly assigned to an expressive writing (EW) or neutral writing (NW) group. Patients in the EW group wrote about their cancer, and patients in the NW group wrote about health behaviors. No statistically significant group differences were found in symptoms of distress, perceived stress, or mood disturbance, except for the Vigor subscale of the Profile of Mood States. However, patients in the EW group reported significantly less sleep disturbance, better sleep quality and sleep duration, and less daytime dysfunction compared with patients in the NW group. The results suggest that EW may have sleep-related health benefits in terminally ill cancer patients.

摘要

42名参与II期临床试验的转移性肾细胞癌患者被随机分配到表达性写作(EW)组或中性写作(NW)组。EW组患者撰写关于他们癌症的内容,NW组患者撰写关于健康行为的内容。除了情绪状态剖面图的活力子量表外,在痛苦症状、感知压力或情绪障碍方面未发现组间有统计学显著差异。然而,与NW组患者相比,EW组患者报告的睡眠障碍明显更少,睡眠质量和睡眠时间更好,白天功能障碍也更少。结果表明,表达性写作可能对晚期癌症患者有与睡眠相关的健康益处。

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