活细胞中的融合孔。
Fusion pore in live cells.
作者信息
Jena Bhanu P
机构信息
Department of Physiology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.
出版信息
News Physiol Sci. 2002 Dec;17:219-22. doi: 10.1152/nips.01394.2002.
PMID:12433973
Abstract
Earlier electrophysiological measurements on live secretory cells suggested the presence of fusion pores at the plasma membrane, where secretory vesicles fuse to release vesicular contents. Recent studies using atomic force microscopy demonstrate for the first time the presence of the fusion pore and reveal its morphology and dynamics at near-nanometer resolution and in real time.
摘要
早期对活分泌细胞进行的电生理测量表明，在质膜上存在融合孔，分泌小泡在此处融合以释放小泡内容物。最近使用原子力显微镜的研究首次证明了融合孔的存在，并以近纳米分辨率实时揭示了其形态和动态。
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