Orloff K G, Dearwent S, Metcalf S, Kathman S, Turner W
Agency for Toxic Substances and Disease Registry, 1600 Clifton Road, MS-E32, Atlanta, Georgia 30333, USA.
Arch Environ Contam Toxicol. 2003 Jan;44(1):125-31. doi: 10.1007/s00244-002-1301-5.
Blood serum concentrations of polychlorinated biphenyls (PCBs) were measured in members of a residential community who lived near a chemical plant that formerly manufactured PCBs. Elevated blood serum PCB concentrations were detected in some of the older adults who were long-term residents of the community. Congener-specific analyses indicated that PCB congeners 153, 138/158, 180, 118, and 187 contributed 60-67% of the total PCBs detected in blood from adults and children. Blood PCB concentrations correlated strongly with age and length of residency in the neighborhood. However, blood PCB concentrations did not correlate with PCB concentrations in soil or house dust samples from the homes. Past exposures to PCBs may be a significant contributor to the elevated PCB concentrations detected in some adult members of the community.
对居住在一家曾生产多氯联苯(PCBs)的化工厂附近的居民区居民进行了血清中多氯联苯浓度的检测。在该社区的一些长期居住的老年人中检测出血清多氯联苯浓度升高。同系物特异性分析表明,多氯联苯同系物153、138/158、180、118和187在成人和儿童血液中检测到的总多氯联苯中占60-67%。血液中多氯联苯浓度与年龄和在该社区居住的时长密切相关。然而,血液中多氯联苯浓度与家中土壤或室内灰尘样本中的多氯联苯浓度并无关联。过去接触多氯联苯可能是该社区一些成年居民中检测到的多氯联苯浓度升高的一个重要因素。