Langer H, Strohmaier W L, Probst S
Abteilung für Anästhesiologie, Klinikum Coburg gGmbH, Germany.
Anaesthesist. 2002 Nov;51(11):914-7. doi: 10.1007/s00101-002-0400-z.
We report on a patient who suffered a large subcapsular and perirenal haematoma after extracorporeal shockwave lithotripsy. Despite surgical intervention the bleeding did not stop for 6 days and 10 units of packed red blood cells were transfused. With the treatment of recombinant, activated factor VIII (NovoSeven((R))) an immediate haemostasis could be reached, so that impending nephrectomy could be avoided. This is the first case where FVIIa has been successfully used to stop a trauma-related bleeding in a patient without any obvious accompanying coagulation disorder.
我们报告了一名患者，其在体外冲击波碎石术后出现了巨大的肾包膜下和肾周血肿。尽管进行了手术干预，但出血6天仍未停止，共输注了10单位的浓缩红细胞。通过使用重组活化因子VIII（诺其（R））进行治疗，实现了即刻止血，从而避免了即将进行的肾切除术。这是首例在没有明显伴随凝血障碍的患者中成功使用FVIIa来止血创伤相关出血的病例。
