Anderer M, Schindler A E, Liebich H M
Arch Gynakol. 1975 Dec 16;220(1):65-72. doi: 10.1007/BF00673149.
Amniotic fluid, maternal vein serum and umbilical cord serum were obtained almost simultaneously from 31 women after an uneventful course of pregnancy. Specimens of amniotic fluid contaminated by blood or meconium were excluded. Creatinine, urea and uric acid were measured by autoanalyser techniques. The concentrations of creatinine, urea and uric acid in amniotic fluid were significantly higher when compared with the levels in maternal vein serum or umbilical cord serum. Between maternal and umbilical cord serum there were only small or no differences. The linear correlations of creatinine, urea and uric acid between maternal and umbilical cord serum were greater than those between amniotic fluid and maternal serum of amniotic fluid and cord serum. It is suggested that the high levels of creatinine, urea and uric acid in amniotic fluid are primarily determined by fetal urine.
在31名孕期过程顺利的女性中，几乎同时获取羊水、母静脉血清和脐带血清。排除被血液或胎粪污染的羊水样本。肌酐、尿素和尿酸通过自动分析仪技术进行测量。与母静脉血清或脐带血清中的水平相比，羊水中肌酐、尿素和尿酸的浓度显著更高。母静脉血清和脐带血清之间只有微小差异或无差异。肌酐、尿素和尿酸在母静脉血清与脐带血清之间的线性相关性大于羊水与母血清或羊水与脐带血清之间的线性相关性。提示羊水中肌酐、尿素和尿酸的高水平主要由胎儿尿液决定。
