Olowe S A, Akinkugbe A, Adewoye H O
Ann Trop Paediatr. 1981 Sep;1(3):161-6. doi: 10.1080/02724936.1981.11748081.
Seven different tests of amniotic fluid have been evaluated for assessment of gestational age. Statistical correlation of the lecithin/sphingomyelin (L/S) ratio with gestational age was positive and significant (P less than 0.001). The Nile blue hydrochloride staining test was very reliable in predicting fetal maturity: in all cases where there was at least 15% of orange-staining cells, the age of the fetus was 37 weeks or more. The reliability of this test was greatly improved when combined with the amniotic fluid L/S ratio, and the result of Clements' "shake test", especially when the creatinine value was also greater than 176 mumol/1. Changes in the levels of amniotic fluid urea, uric acid and total protein were not sufficiently consistent to be of value in assessing fetal maturity. Where facilities for ultrasound are not available, these simple tests can be very helpful in the determination of fetal maturity and in the prevention of accidental delivery of immature fetuses.
为评估孕周，已对七种不同的羊水检测方法进行了评估。卵磷脂/鞘磷脂（L/S）比值与孕周的统计相关性呈正且显著（P小于0.001）。盐酸尼罗蓝染色试验在预测胎儿成熟度方面非常可靠：在所有橙色染色细胞至少占15%的病例中，胎儿年龄为37周或更大。当与羊水L/S比值以及克莱门茨“振荡试验”结果相结合时，尤其是当肌酐值也大于176μmol/1时，该试验的可靠性大大提高。羊水尿素、尿酸和总蛋白水平的变化不够一致，在评估胎儿成熟度方面无价值。在没有超声设备的情况下，这些简单的检测方法在确定胎儿成熟度以及预防未成熟胎儿意外分娩方面非常有帮助。
