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在美国海军服役的年轻人中的结核病感染情况。

Tuberculosis infection among young adults enlisting in the United States Navy.

作者信息

Smith Besa, Ryan Margaret A K, Gray Gregory C, Polonsky James M, Trump David H

机构信息

Department of Defense Center for Deployment Health Research at the Naval Health Research Center, San Diego, CA 92186-5122, USA.

出版信息

Int J Epidemiol. 2002 Oct;31(5):934-9. doi: 10.1093/ije/31.5.934.

Abstract

BACKGROUND

Tuberculosis (TB) is a re-emerging infectious disease threat worldwide. To protect the health and readiness of US military personnel, policies exist to screen for and treat latent TB infection at the time of service entrance.

RESULTS

of this screening programme have not been recently described.

METHODS

Multivariate regression techniques were used to evaluate demographic and medical data associated with TB infection among all young adults entering US Navy enlisted service between 1 October 1997 and 30 September 1998. Results A total of 44,128 adults (ages 17-35, 81% male) were screened for TB during this 12-month period. The prevalence of latent TB infection was 3.5%. Place of birth was very strongly associated with TB infection, with foreign-born recruits eight times more likely to have a reactive tuberculin skin test or history of infection. Those who reported their race as 'Asian/Pacific Island' had 3.8 times the odds of having evidence of TB infection compared with 'Caucasian' recruits, even after adjusting for place of birth.

CONCLUSIONS

The prevalence of TB infection among Navy recruits was last reported as 2.5% nearly 10 years ago. The apparent increase to 3.5% in this large cohort is likely due to a concurrent increase in the number of foreign-born recruits, and it serves to underscore the importance of comprehensive screening and treatment of latent TB infections in this population.

摘要

背景

结核病是一种在全球范围内再度出现的传染病威胁。为保护美国军事人员的健康和备战状态,制定了在入伍时筛查和治疗潜伏性结核感染的政策。

结果

该筛查项目的结果近期未被描述。

方法

采用多变量回归技术评估1997年10月1日至1998年9月30日期间所有进入美国海军服役的年轻成年人中与结核感染相关的人口统计学和医学数据。结果在这12个月期间,共对44,128名成年人(年龄17 - 35岁,81%为男性)进行了结核病筛查。潜伏性结核感染的患病率为3.5%。出生地与结核感染密切相关,外国出生的新兵结核菌素皮肤试验呈阳性或有感染史的可能性是本土出生新兵的八倍。那些将自己的种族报告为“亚洲/太平洋岛民”的新兵,即使在调整出生地因素后,有结核感染证据的几率是“白种人”新兵的3.8倍。

结论

近10年前海军新兵中结核感染的患病率报告为2.5%。在这个大型队列中患病率明显增至3.5%,可能是由于外国出生新兵数量同时增加,这凸显了对该人群潜伏性结核感染进行全面筛查和治疗的重要性。

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