Scheuler W, Spreng M
Arch Otorhinolaryngol. 1975 Oct 30;211(1):5-16. doi: 10.1007/BF00467285.
In agreement with earlier experiments an increase of amplitude of the medium components (80-250 ms: Non-Pon) with decreasing repetition rate or increasing interval between the stimuli (sinusoidal tones, white noise, craftsman noise) is observed. There is no influence of the variable intervals upon the off-effect, if sinusoidal tones and white noise are used. A small increase of the amplitude difference Noff-Poff results if bursts of craftsman noise are used for stimulation. The amplitude of a peak in the range 300-400 ms which can be regarded approximatively as the peak of the long lasting dc-component, related to the positive peak (Pon) around 200 ms shows also an increasing tendency if the interval between stimuli is enlarged. Pon itself is augmented if related to the preceding section before stimulus on-set. Therefore the increase of the slow component expresses only an increase of the positive component Pon or is based upon a dc-shift which is added to the preceding section as well as to the range of the dc-component beginning around 300 ms after stimulus on-set. Using only sinusoidal tones a reduction takes place of the amplitude of the potential evoked by a tone of constant duration if the silent pauses are smaller than 2500 ms. If the pause preceding a tone of constant duration is reduced down to 300 ms the decrease of the amplitude is around 50-60%. The amplitude of the off-effect however is not affected. Only if related on the positive component Pon the slow component shows a small decrease. If related on the preceding section there is no change caused by different pauses preceding a tone of constant duration. Both, the latency of on- and off-components is also not influenced by the variable pause. Only the peak of the slow component shows a shift in the way that there is a maximum if the duration of the pause corresponds to half of the interval. In this case there is also a clear maximum of the amplitude of the potential evoked by the tone of variable duration. The results throw some light upon the different origin of the components of the evoked response and the overlapping of dc-shifts.
与早期实验一致，观察到随着重复率降低或刺激（正弦音、白噪声、工匠噪声）之间的间隔增加，中等成分（80 - 250毫秒：非波恩成分）的振幅增大。如果使用正弦音和白噪声，可变间隔对关效应没有影响。如果使用工匠噪声脉冲进行刺激，关-开振幅差会有小幅增加。在300 - 400毫秒范围内的一个峰值的振幅，如果将其近似视为持久直流成分的峰值，与200毫秒左右的正峰值（波恩）相关，当刺激间隔增大时也显示出增加的趋势。如果与刺激开始前的前一段相关，波恩本身会增大。因此，慢成分的增加仅表示正成分波恩的增加，或者是基于一个直流偏移，该偏移既添加到前一段，也添加到刺激开始后约300毫秒开始的直流成分范围内。如果仅使用正弦音，当静音间隔小于2500毫秒时，持续时间恒定的音调诱发的电位振幅会降低。如果将持续时间恒定的音调之前的间隔减小到300毫秒，振幅的降低约为50 - 60%。然而，关效应的振幅不受影响。只有与正成分波恩相关时，慢成分才会有小幅下降。如果与前一段相关，持续时间恒定的音调之前不同的间隔不会引起变化。开和关成分的潜伏期也都不受可变间隔的影响。只有慢成分的峰值会有偏移，即当间隔持续时间对应于间隔的一半时会出现最大值。在这种情况下，可变持续时间的音调诱发的电位振幅也会有明显的最大值。这些结果揭示了诱发反应成分的不同起源以及直流偏移的重叠情况。
