Zaítsev A V, Rozenshtraukh L V, Sharifov O F, Kaliadin A Iu, Schuessler R B, Beloshapko G G, Iushmanova A V, Boineau J P
Ross Fiziol Zh Im I M Sechenova. 1997 Mar;83(3):15-40.
Epicardial mapping (254 unipolar electrodes) of the dog heart both atria was performed to determine spatial distribution of arrhythmic events. The mapping showed that the first atrial premature depolarisation (APD) emerged from ectopic foci, it showed also specific multifocal patterns suggesting a septal source of tachycardia. The data obtained suggests that vagal stimulation (VS) induces focal ectopic APDs, that APDs and escape beats may be due to the same mechanism of spontaneous depolarization in the absence of a reset from dominant rhythm, that a single VS-induced APD is sufficient for initiation of a reentrant atrial fibrillation.
采用心外膜标测法（254个单极电极）对犬心脏的两个心房进行标测，以确定心律失常事件的空间分布。标测结果显示，首个房性早搏去极化（APD）源自异位起搏点，还呈现出特定的多灶性模式，提示心动过速的起源部位在间隔。所获数据表明，迷走神经刺激（VS）可诱发局灶性异位APD，在未受主导节律重置的情况下，APD和逸搏可能源于相同的自发去极化机制，单次VS诱发的APD足以引发折返性心房颤动。
