Extensive fixed drug eruption to nimesulide with cross-sensitivity to sulfonamides in a child.

Nimesulide, a new nonsteroidal anti-inflammatory drug with a favorable tolerability profile, is being used increasingly in pediatric practice. Its common side effects pertain to the gastrointestinal tract and central nervous system. The common cutaneous adverse effects are pruritus and skin rash. Rarely purpura and fixed drug eruptions have also been observed in adults. We present herein a case of nimesulide-induced fixed drug eruption in a 10-year-old boy. The lesions were extensive and showed cross-sensitivity to sulfonamides.