Tai F H
Zhonghua Min Guo Wei Sheng Wu Xue Za Zhi. 1975 Sep;8(3):207-12.
During the 1971 outbreaks of acute hemorrhagic conjunctivitis, 298 cases were admitted to the Veterans General Hospital and seven strains of new picornavirus were isolated in human epidermoid carcinoma cells. Two strains of the virus isolated have been further studied. Serological neutralization indicated that these isolates might represent a distinct picornavirus group. Biophysical and biological properties determined by this study indicated that the viruses had many characteristics in common with the echoviruses such as morphological appearance, lack of essential lipids, acid stability, density in cesium chloride, sedimentation rate, growth in the presence of 5-iodo-2-deoxyuridine 5-bromo-2-deoxyuridine and nonpathogenicity to suckling mice. However, they were differentiated into 2 strains on the basis of plaque size and neutralization kinetics.
在1971年急性出血性结膜炎暴发期间，298例患者被收治于荣民总医院，并且在人表皮样癌细胞中分离出7株新型小核糖核酸病毒。已对分离出的2株病毒进行了进一步研究。血清学中和试验表明，这些分离株可能代表一个独特的小核糖核酸病毒群。本研究确定的生物物理和生物学特性表明，这些病毒与艾柯病毒有许多共同特征，如形态外观、缺乏必需脂质、酸稳定性、在氯化铯中的密度、沉降率、在5-碘-2-脱氧尿苷和5-溴-2-脱氧尿苷存在下的生长情况以及对乳鼠无致病性。然而，根据蚀斑大小和中和动力学，它们被分为2个毒株。
