Bail Hermann J, Kolbeck Stefan, Krummrey Gert, Weiler Andreas, Windhagen Henning J, Hennies Karolin, Raun Kirsten, Raschke Michael J
Clinic for Trauma and Reconstructive Surgery, Charité, Campus Virchow Clinic, Humboldt University, Berlin, Germany.
Clin Orthop Relat Res. 2002 Nov(404):362-7. doi: 10.1097/00003086-200211000-00053.
Assessing the regenerate strength in distraction osteogenesis is crucial for clinical treatment. Several methods have been used to achieve this, including plain radiography, digital radiography, quantitative computed tomography, dual energy xray absorptiometry, and ultrasound. The aim of the current study was to investigate the use of ultrasound in monitoring regenerate formation and to correlate this to biomechanical testing results. An osteotomy was done on the tibia of 30 Yucatan micropigs and an Ilizarov-type half-ring external fixator was mounted. After a 5-day latency period, the tibias were distracted for 10 days and then left to consolidate for 10 days. Seven ultrasound examinations were done during Day 15 through Day 25. After sacrifice, the bone mineral density was measured using quantitative computed tomography. Maximum load and torsional stiffness were measured and correlated with ultrasound measurements and bone mineral density. The ultrasound penetration depth and the bone mineral density correlated closely with torsional stiffness. Ultrasound can be a noninvasive predictor of bone regenerate strength in the early phase of distraction osteogenesis, which may reduce the need for radiographs.
评估牵张成骨术中再生骨强度对于临床治疗至关重要。已经使用了多种方法来实现这一目标，包括普通X线摄影、数字X线摄影、定量计算机断层扫描、双能X线吸收法和超声检查。本研究的目的是探讨超声在监测再生骨形成中的应用，并将其与生物力学测试结果相关联。对30只尤卡坦小型猪的胫骨进行截骨，并安装Ilizarov型半环外固定器。经过5天的延迟期后，对胫骨进行10天的牵张，然后让其巩固10天。在第15天至第25天期间进行了7次超声检查。处死后，使用定量计算机断层扫描测量骨密度。测量最大负荷和扭转刚度，并将其与超声测量结果和骨密度相关联。超声穿透深度和骨密度与扭转刚度密切相关。超声可以作为牵张成骨早期骨再生强度的无创预测指标，这可能会减少对X线片的需求。
