一名绝经后女性的息肉样子宫内膜腺肌瘤，酷似宫颈癌，与卵巢卵泡膜瘤相关。

Polypoid endometrial adenomyoma in a postmenopausal woman, mimicking cervical cancer, associated with ovarian thecoma.

作者信息

Horn L-C, Fischer U, Höckel M

机构信息

Institute of Pathology, University of Leipzig, Liebigstrasse 26, D-04103 Leipzig, Germany.

出版信息

Arch Gynecol Obstet. 2002 Dec;267(2):101-3. doi: 10.1007/s00404-001-0253-8.

DOI:10.1007/s00404-001-0253-8

PMID:12439557

Abstract

PURPOSE

Atypical polypoid adenomyoma (APA) usually occurs in premenopausal women and arises from the endometrium. APAs protruding into the external os may lead to diagnostic problems.

CASE

We present a case of APA in a 62-year-old postmenopausal woman, prolapsing through the external os, clinically mimicking cervical cancer FIGO IB2 (4.5 cmx3 cmx3 cm). Histologically the tumor was composed of endometrioid-like with slight cellular atypia and endocervical-type mucinous glands admixed with smooth muscle bundles, exhibiting low Ki-67 antigen immunostaining. The the left adnexa contained an ovarian thecoma.

CONCLUSIONS

To the best of our knowledge, this is the first case of APA in a postmenopausal woman, mimicking cervical cancer and associated with ovarian thecoma. Pathogenetically it is proposed, that hyperestrogenism and, in the present case accompanied by progestin production of questionable source, may play an important role in the development of APAs with the admixture of endometrial and endocervical glands.

摘要