Dehnert C, Hütler M, Liu Y, Menold E, Netzer C, Schick R, Kubanek B, Lehmann M, Böning D, Steinacker J M
Dept. of Sports and Rehabilitation Medicine, Medical Centre, University of Ulm, Germany.
Int J Sports Med. 2002 Nov;23(8):561-6. doi: 10.1055/s-2002-35533.
The purpose of our study was to evaluate hematologic acclimatization during 2 weeks of intensive normoxic training with regeneration at moderate altitude (living high-training low, LHTL) and its effects on sea-level performance in well trained athletes compared to another group of equally trained athletes under control conditions (living low - training low, CONTROL). Twenty-one triathletes were ascribed either to LHTL (n = 11; age: 23.0 +/- 4.3 yrs; VO 2 max: 62.5 +/- 9.7 [ml x min -1 x kg -1]) living at 1956 m of altitude or to CONTROL (n = 10; age: 18.7 +/- 5.6 yrs; VO 2 max: 60.5 +/- 6.7 ml x min -1 x kg -1) living at 800 m. Both groups performed an equal training schedule at 800 m. VO 2 max, endurance performance, erythropoietin in serum, hemoglobin mass (Hb tot, CO-rebreathing method) and hematological quantities were measured. A tendency to improved performance in LHTL after the camp was not significant (p < 0.07). Erythropoietin concentration increased temporarily in LHTL (Delta 14.3 +/- 8.7 mU x ml -1; p < 0.012). Hb tot remained unchanged in LHTL whereas was slightly decreased from 12.5 +/- 1.3 to 11.9 +/- 1.3g x kg -1 in CONTROL (p < 0.01). As the reticulocyte number tended to higher values in LHTL than in CONTROL, it seems that a moderate stimulation of erythropoiesis during regeneration at altitude served as a compensation for an exercise-induced destruction of red cells.
我们研究的目的是评估在中等海拔地区进行2周强化常氧训练并再生（高住低练，LHTL）期间的血液学适应情况，以及与另一组在对照条件下（低住低练，CONTROL）同等训练的运动员相比，其对训练有素的运动员海平面成绩的影响。21名铁人三项运动员被分配到LHTL组（n = 11；年龄：23.0 +/- 4.3岁；最大摄氧量：62.5 +/- 9.7 [ml·min⁻¹·kg⁻¹]），居住在海拔1956米处，或CONTROL组（n = 10；年龄：18.7 +/- 5.6岁；最大摄氧量：60.5 +/- 6.7 ml·min⁻¹·kg⁻¹），居住在海拔800米处。两组在海拔800米处执行相同的训练计划。测量了最大摄氧量、耐力表现、血清促红细胞生成素、血红蛋白量（Hb tot，一氧化碳再呼吸法）和血液学指标。训练营后LHTL组成绩改善的趋势不显著（p < 0.07）。LHTL组促红细胞生成素浓度暂时升高（Δ14.3 +/- 8.7 mU·ml⁻¹；p < 0.012）。LHTL组Hb tot保持不变，而CONTROL组则从12.5 +/- 1.3降至11.9 +/- 1.3g·kg⁻¹（p < 0.01）。由于LHTL组网织红细胞数量倾向于高于CONTROL组，似乎在海拔再生期间对红细胞生成的适度刺激起到了补偿运动诱导的红细胞破坏的作用。
