原发性巨细胞病毒感染的免疫功能正常受试者中，单克隆丙种球蛋白病的发生率较高。
High rate of monoclonal gammopathy among immunocompetent subjects with primary cytomegalovirus infection.
作者信息
Bühler Suvi, Laitinen Kalevi, Holthöfer Harry, Järvinen Asko, Schauman Knut-Olof, Hedman Klaus
机构信息
Department of Virology, Helsinki University Central Hospital, FIN-00029 HUCH, Helsinki, Finland.
出版信息
Clin Infect Dis. 2002 Dec 1;35(11):1430-3. doi: 10.1086/344465. Epub 2002 Nov 11.
Serum samples from immunocompetent adults with primary cytomegalovirus (CMV) or Epstein-Barr virus (EBV) infection and from solid-organ or bone marrow transplant recipients with primary CMV infection were examined for paraproteins. Several immunocompetent patients with CMV infection but none with EBV infection presented with an M component, which implies that the M component connects CMV infection to a risk of B cell malignancy.
对具有免疫活性的原发性巨细胞病毒（CMV）或爱泼斯坦-巴尔病毒（EBV）感染的成年人以及原发性CMV感染的实体器官或骨髓移植受者的血清样本进行副蛋白检测。数名具有CMV感染的免疫活性患者出现了M成分，但EBV感染患者均未出现，这意味着M成分将CMV感染与B细胞恶性肿瘤风险联系起来。
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