Karam Elie G, Yabroudi Philippe F, Melhem Nadine M
Institute for Research, Development and Applied Care (IDRAC), Beirut, Beirut, Lebanon.
Compr Psychiatry. 2002 Nov-Dec;43(6):463-8. doi: 10.1053/comp.2002.35910.
This is the first published study from an Arab Near Eastern country to examine the comorbidity of substance abuse with other psychiatric disorders. All inpatients with substance abuse/dependence (present or past) admitted to the psychiatry unit at St. George Hospital (Lebanon) between 1979 and 1992 (N = 222) constituted the study sample. Of these, 64.9% were found to have comorbid psychiatric disorders with specific relations between individual substances and psychiatric diagnoses identified such as cocaine and bipolar disorder (42.1%), and cannabis and schizophrenia (44.8%). Patients with no axis I disorder were predominantly heroin users, most of them having antisocial personality disorder. Polydrug abuse was found among 44.9% of patients, and most of the benzodiazepine abusers belonged to this category. The pattern of comorbidity of psychiatric and substance use disorders in this Near East inpatient population compares well with findings from the Western hemisphere: cultural factors (including war) do not seem to have much of an effect on the different forms of dual diagnoses. This adds weight to the already existing literature on the need for careful psychiatric assessment in the treatment of substance abuse.
这是来自一个阿拉伯近东国家的首篇已发表研究,旨在探讨药物滥用与其他精神障碍的共病情况。1979年至1992年间,入住圣乔治医院(黎巴嫩)精神科病房的所有药物滥用/依赖患者(当前或既往)(N = 222)构成了研究样本。其中,64.9%的患者被发现患有共病精神障碍,且确定了个体药物与精神诊断之间的特定关系,如可卡因与双相情感障碍(42.1%),以及大麻与精神分裂症(44.8%)。无轴I障碍的患者主要是海洛因使用者,他们中的大多数患有反社会人格障碍。44.9%的患者存在多药滥用情况,大多数苯二氮䓬类药物滥用者属于这一类别。该近东住院患者群体中精神障碍与物质使用障碍的共病模式与西半球的研究结果相当:文化因素(包括战争)似乎对不同形式的双重诊断影响不大。这进一步支持了现有文献中关于在药物滥用治疗中进行仔细精神评估必要性的观点。