Aziah M S Noor, Rosnah T, Mardziah A, Norzila M Z
Department of Paediatrics, Institut Pediatrik, Hospital Kuala Lumpur, Dermatology Department, Hospital Kuala Lumpur, 50580, Kuala Lumpur.
Med J Malaysia. 2002 Sep;57(3):329-39.
Atopic dermatitis is the commonest skin disease in children, causing psychological, social and functional disability to them and their families. This study assessed the family impact and quality of life using the translated Malay version of The Dermatology Family Impact (DFI) and The Children's Dermatology Life Quality Index (CDLQI) questionnaires. Seventy-two children, aged between 6 months and 16 years attending the Paediatric Dermatology Clinic at the Paediatric Institute and the Dermatology Department, Hospital Kuala Lumpur participated in this study. Thirty-nine patients (54.2%) were males and 33 patients (45.8%) were females. The median age of the patients was 74 months (Q1 6, Q3 104 months). The median age of diagnosis was 22 months (Q1 1, Q3 36 months). The median disease duration was 44 months (Q1 3, Q3 65). The severity of eczema was assessed using the SCORAD severity index (maximum score = 83). The median SCORAD (European Task Force On Atopic Dermatitis) score was 36 (n = 72, SD = 16.2). The majority of patients in this study suffered from moderately severe eczema (n = 40, mean, SCORAD = 29.3) followed by severe eczema (n = 27, mean SCORAD = 54.3). The mildly affected patients formed the minority group (n = 5, mean SCORAD = 9.0). The family impact was shown to be greater in severe atopic dermatitis compared to moderate atopic dermatitis (Anova, p = 0.02). The children's quality of life impairment was also greater in severe atopic dermatitis compared to moderate atopic dermatitis (Anova p = 0.08). This study confirms that quality of life and family impact are related to the severity of atopic dermatitis.
特应性皮炎是儿童最常见的皮肤病，给患儿及其家庭带来心理、社交和功能障碍。本研究使用马来语翻译版的《皮肤病学家庭影响问卷》（DFI）和《儿童皮肤病生活质量指数问卷》（CDLQI）评估家庭影响和生活质量。72名年龄在6个月至16岁之间的儿童参与了本研究，他们在儿科研究所的儿科皮肤科诊所和吉隆坡医院皮肤科就诊。39名患者（54.2%）为男性，33名患者（45.8%）为女性。患者的中位年龄为74个月（第一四分位数6，第三四分位数104个月）。诊断的中位年龄为22个月（第一四分位数1，第三四分位数36个月）。疾病的中位持续时间为44个月（第一四分位数3，第三四分位数65）。使用SCORAD严重程度指数评估湿疹的严重程度（最高分 = 83）。中位SCORAD（欧洲特应性皮炎工作组）评分为36（n = 72，标准差 = 16.2）。本研究中的大多数患者患有中度严重湿疹（n = 40，平均SCORAD = 29.3），其次是重度湿疹（n = 27，平均SCORAD = 54.3）。轻度受累患者构成少数群体（n = 5，平均SCORAD = 9.0）。与中度特应性皮炎相比，重度特应性皮炎的家庭影响更大（方差分析，p = 0.02）。与中度特应性皮炎相比，重度特应性皮炎患儿的生活质量受损也更大（方差分析p = 0.08）。本研究证实，生活质量和家庭影响与特应性皮炎的严重程度相关。
