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坏死性梭菌性肠炎与叠加于缺血性肠病的继发性梭菌感染

Clostridial enteritis necroticans versus secondary clostridial infection superimposed upon ischemic bowel disease.

作者信息

Zhao Weiqiang, Daroca Philip J, Crawford Byron E

机构信息

Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.

出版信息

J La State Med Soc. 2002 Sep-Oct;154(5):251-5.

Abstract

Clostridial enteritis necroticans, or pig-bel, as seen in Papua New Guinea, is a necrotizing, segmental gangrene of the small intestine occurring in members of a malnourished population, who become ill after consuming large quantities of pork contaminated with Type C. Clostridium perfringens. We report a case of possible Clostridial enteritis necroticans with concomitant ischemic intestinal disease secondary to superior mesenteric arterial thrombosis occurring in a 53-year-old woman with a long history of diabetes mellitus, hypertension, and peripheral vascular disease. The differential diagnosis and the pathogenesis of C. perfringens enteritis necroticans are discussed.

摘要

坏死性梭菌性肠炎,即巴布亚新几内亚所见的“猪瘟”,是一种发生于营养不良人群的小肠坏死性、节段性坏疽,这些人在食用大量被C型产气荚膜梭菌污染的猪肉后发病。我们报告一例可能的坏死性梭菌性肠炎病例,该病例伴有继发于肠系膜上动脉血栓形成的缺血性肠道疾病,患者为一名53岁女性,有长期糖尿病、高血压和周围血管疾病史。文中讨论了产气荚膜梭菌坏死性肠炎的鉴别诊断和发病机制。

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