Bratchik A M
Probl Gematol Pereliv Krovi. 1975 Jun;20(6):18-22.
Fibrinolysic cadaveric blood studied after a rapid death (strangulation asphyxia, traumatic and sudden death) contained no plasmin--an enzyme of fibrin destruction, and no plasminogen--its inactive precursor. In the absence of plasmin and plasminogen of interest is a high content of plasminogen activator. An increase in the content of the activator in the fibrinolysic blood exists along with a marked proactivator level. A relationshp between the concentration of the activator and the proactivator in this blood indirectly pointed to the intravascular (from the pre-existing blood proactivator of the living), and not the tissue origin of the activator. Activation of plasma proactivator is caused by the entrance of tissue lysokinases into the circulation.
对快速死亡（绞窄性窒息、外伤性猝死）后的尸体纤溶血液进行研究发现，其中不含纤溶酶——一种破坏纤维蛋白的酶，也不含纤溶酶原——其无活性前体。在缺乏纤溶酶和纤溶酶原的情况下，有趣的是纤溶酶原激活剂含量很高。纤溶血液中激活剂含量的增加与显著的前激活剂水平同时存在。这种血液中激活剂和前激活剂浓度之间的关系间接表明激活剂来源于血管内（来自生前已存在的血液前激活剂），而非组织来源。血浆前激活剂的激活是由组织溶激酶进入循环系统所致。
