氧化吲哚生物碱阿枯米辛的对映体特异性、立体特异性全合成。
Enantiospecific, stereospecific total synthesis of the oxindole alkaloid alstonisine.
作者信息
Wearing Xiangyu Z, Cook James M
机构信息
Department of Chemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, USA.
出版信息
Org Lett. 2002 Nov 28;4(24):4237-40. doi: 10.1021/ol020170b.
PMID:12443067
Abstract
[reaction: see text] The total synthesis of alstonisine was accomplished in enantiospecific fashion in an overall yield of 12% (from tryptophan methyl ester) in 17 reaction vessels. The structure of alstonisine (1) has been determined by NOE spectroscopic experiments and was confirmed by single-crystal X-ray analysis.
摘要
[反应：见正文] 阿斯顿宁以对映体特异性方式全合成，从色氨酸甲酯开始，在17个反应容器中总产率为12%。阿斯顿宁（1）的结构已通过NOE光谱实验确定，并经单晶X射线分析证实。
Zotero 插件