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凝聚在一起:古菌中的染色质。

Holding it together: chromatin in the Archaea.

作者信息

White Malcolm F, Bell Stephen D

机构信息

Centre for Biomolecular Sciences, St Andrews University, North Haugh, St Andrews, KY16 9ST, Fife, UK.

出版信息

Trends Genet. 2002 Dec;18(12):621-6. doi: 10.1016/s0168-9525(02)02808-1.

Abstract

Recently, several advances have been made in the understanding of the form and function of archaeal chromatin. Remarkable parallels can be drawn between the structure and modification of chromatin components in the archaeal and the eukaryotic domains of life. Indeed, it now appears that key components of the hugely complex eukaryotic chromatin regulatory machinery were established before the divergence of the archaeal and eukaryotic lineages.

摘要

最近,在对古细菌染色质的形式和功能的理解方面取得了一些进展。在古细菌和真核生物生命域中,染色质成分的结构和修饰之间可以得出显著的相似之处。事实上,现在看来,极其复杂的真核染色质调控机制的关键成分在古细菌和真核生物谱系分化之前就已确立。

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