Haritoglou C, Neubauer A S, Herzum H, Freeman W R, Mueller A J
Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.
Br J Ophthalmol. 2002 Dec;86(12):1390-4. doi: 10.1136/bjo.86.12.1390.
To report on the intraindividual and interindividual variability of tumour size (height and base diameter) measurements using standardised echography in a masked prospective study.
20 consecutive eyes of 20 patients were examined on four different visits by three experienced examiners using standardised echography. As common in standardised echography, tumour height was evaluated with A-scan technique, while transverse and longitudinal base diameter were calculated with B-scan.
Tumour height measurements using A-scan were more accurate than base diameter measurements using B-scan. The standard deviation for tumour height over all visits/measurements was 0.18 mm (A-scan), 0.79 mm for transverse, and 0.69 mm for longitudinal base diameters (B-scan). The interclass correlation coefficient (ICC) was much higher for tumour height measurements with A-scan (0.7735 for three examiners on one visit) than for transverse (0.6563) or longitudinal (0.4522) base diameter measurements with B-scan techniques.
A-scan techniques for tumour height measurements provide very reproducible results with little intraindividual and interobserver variability. As B-scan techniques for tumour base evaluation are less accurate they should be used for topographic and morphological examinations.
在一项盲法前瞻性研究中，报告使用标准化超声检查测量肿瘤大小（高度和基底直径）的个体内和个体间变异性。
由三名经验丰富的检查者使用标准化超声检查，在四次不同的检查中对20例患者的20只眼睛进行连续检查。在标准化超声检查中，通常用A超技术评估肿瘤高度，而用B超计算横向和纵向基底直径。
使用A超测量肿瘤高度比使用B超测量基底直径更准确。在所有检查/测量中，肿瘤高度的标准差为0.18毫米（A超），横向基底直径为0.79毫米，纵向基底直径为0.69毫米（B超）。A超测量肿瘤高度的组内相关系数（ICC）（一次检查中三名检查者的ICC为0.7735）远高于B超技术测量横向（0.6563）或纵向（0.4522）基底直径的ICC。
用于测量肿瘤高度的A超技术可提供非常可重复的结果，个体内和观察者间变异性很小。由于用于评估肿瘤基底的B超技术准确性较低，因此应将其用于地形学和形态学检查。
