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标准化超声检查在前房段肿瘤中辅助超声生物显微镜检查的可能作用:一项对13例患者的系列研究

Possible role of standardized echography complementing ultrasound biomicroscopy in tumors of the anterior eye segment: a study in a series of 13 patients.

作者信息

Kuzmanović Elabjer B, Bušić M, Miletić D, Bjeloš M, Vukojević N, Bosnar D

机构信息

Faculty of Medicine, University Eye Clinic, Josip Juraj Strossmayer University of Osijek, University Hospital "Sveti Duh", Sveti Duh 64, Zagreb, Croatia.

University Eye Clinic, University Hospital Centre Zagreb, Zagreb, Croatia.

出版信息

J Ultrasound. 2018 Sep;21(3):209-215. doi: 10.1007/s40477-018-0301-x. Epub 2018 May 17.

Abstract

PURPOSE

To evaluate the efficacy of standardized A-scan echography (ASE) complementing ultrasound biomicroscopy (UBM) to propose the most efficient method as grounds for the diagnosis, treatment, and follow-up of anterior eye-segment tumors.

METHODS

The inclusion criteria were tumors of the ciliary body and peripheral choroidal tumors, whose anterior border could not be visualized with a 10 MHz ultrasound probe. The largest basal dimension and the highest prominence of the tumor were measured with a UBM Lin 50 probe. A standardized A-scan examination determined the tumor's thickness and internal reflectivity. Thus, tissue differentiation led to a standardized echography-based diagnosis (SED).

RESULTS

The study included 13 patients. SED was achieved in all examined tumors. The smallest thickness of the tumor of the ciliary body enabling SED was only 1.78 mm. The highest prominence of the tumor (3.66 ± 1.39 mm) was generally larger than its thickness (3.30 ± 1.71 mm).

CONCLUSION

When approaching ciliary body tumors, both ASE and UBM should be performed, the former to accurately differentiate the tumor and measure its height, and the latter to delineate anterior tumor margins and iris involvement. Standardized echography-based diagnosis was grounds for further evaluation and/or treatment in this case series. The highest prominence of the ciliary body tumor perpendicular to the sclera as evidenced by UBM was generally higher than the thickness obtained with standardized echography. Hence, we propose ASE thickness to be the grounds for staging the severity of ciliary body tumors in the algorithm for their management.

摘要

目的

评估标准化A超超声检查(ASE)辅助超声生物显微镜检查(UBM)的有效性,以提出最有效的方法作为眼前节肿瘤诊断、治疗和随访的依据。

方法

纳入标准为睫状体肿瘤和周边脉络膜肿瘤,其前缘无法用10MHz超声探头显示。使用UBM Lin 50探头测量肿瘤的最大基底尺寸和最高突出度。标准化A超检查确定肿瘤的厚度和内部反射率。因此,组织分化得出基于标准化超声检查的诊断(SED)。

结果

该研究纳入13例患者。所有检查的肿瘤均实现了SED。能够实现SED的睫状体肿瘤的最小厚度仅为1.78mm。肿瘤的最高突出度(3.66±1.39mm)通常大于其厚度(3.30±1.71mm)。

结论

在处理睫状体肿瘤时,应同时进行ASE和UBM检查,前者用于准确鉴别肿瘤并测量其高度,后者用于描绘肿瘤前缘和虹膜受累情况。在本病例系列中,基于标准化超声检查的诊断是进一步评估和/或治疗的依据。UBM显示的垂直于巩膜的睫状体肿瘤的最高突出度通常高于标准化超声检查测得的厚度。因此,我们建议将ASE测量的厚度作为睫状体肿瘤管理算法中分期严重程度的依据。

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