子宫内膜癌中的睾酮代谢

Testosterone metabolism in endometrial cancer.

作者信息

Calanog A, Sall S, Gordon G G, Olivo J, Southren A L

出版信息

Am J Obstet Gynecol. 1976 Jan 1;124(1):60-3. doi: 10.1016/0002-9378(76)90012-0.

DOI:10.1016/0002-9378(76)90012-0

Abstract

Plasma testosterone (PCT), metabolic clearance (MCRT), and production rates (PRT) of testosterone and conversion ratio of testosterone to androstenedione (CRppTA) were performed on 11 patients with endometrial cancer and on a control group of five postmenopausal women. The PCT, MCRT, and PRT of patients with endometrial cancer are in the normal postmenopausal range. The conversion of testosterone to androstenedione in patients with endometrial cancer was significantly decreased.

摘要

对11例子宫内膜癌患者及5名绝经后女性组成的对照组进行了血浆睾酮（PCT）、代谢清除率（MCRT）、睾酮生成率（PRT）以及睾酮向雄烯二酮的转化率（CRppTA）检测。子宫内膜癌患者的PCT、MCRT和PRT处于绝经后的正常范围内。子宫内膜癌患者中睾酮向雄烯二酮的转化显著降低。

相似文献

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Testosterone metabolism in endometrial cancer.子宫内膜癌中的睾酮代谢

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