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来自荷兰的耐氟喹诺酮临床大肠杆菌分离株的系统发育背景和毒力谱

Phylogenetic background and virulence profiles of fluoroquinolone-resistant clinical Escherichia coli isolates from the Netherlands.

作者信息

Johnson James R, van der Schee Cindy, Kuskowski Michael A, Goessens Wil, van Belkum Alex

机构信息

Medical Service, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA.

出版信息

J Infect Dis. 2002 Dec 15;186(12):1852-6. doi: 10.1086/345767. Epub 2002 Nov 22.

DOI:10.1086/345767
PMID:12447775
Abstract

Thirteen fluoroquinolone-resistant Escherichia coli (FQREC) isolates from hospitalized patients in the Netherlands were found to represent predominantly (low-virulence) phylogenetic groups A and B1 and to lack extraintestinal virulence traits. These FQREC resemble animal-source E. coli and presumably pose little threat to noncompromised hosts. Similar analysis of other FQREC is needed.

摘要

在荷兰，从住院患者身上分离出的13株耐氟喹诺酮大肠杆菌（FQREC）菌株主要属于（低毒力）系统发育群A和B1，且缺乏肠道外毒力特征。这些FQREC与动物源大肠杆菌相似，可能对未受损害的宿主几乎不构成威胁。需要对其他FQREC进行类似分析。

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