Szabóová E, Donic V, Albertová D, Turciansky M, Tomori Z
Ustav patofyziológie, Lekárskej fakulty Univerzity P.J. Safárika, Tr. SNP 1, 040 66 Kosice, Slovak Republic.
Sb Lek. 2002;103(1):79-83.
The occurrence of cardiac dysrhythmias have been analysed in 16 adult patients suffering from obstructive sleep apnea syndrome of various severity randomly selected from more than 300 persons examined in our sleep laboratory from 1996 with a complex polysomnography Alice 3 (Healthdyne). The number of apneic episodes emerging in the first, second and third part of sleep was practically the same although their duration prolonged during the night culminating with an average of 25 sec (p < 0.02). OSA episodes caused a decrease of oxyhaemoglobin saturation to lower values during REM compared to NREM sleep (76.1% versus 81.7%, p < 0.05). Cardiac dysrhythmias occurred more frequently during and immediately after, than before OSA episodes demonstrating their causal relations.
对1996年以来在我们睡眠实验室接受检查的300多人中随机挑选出的16例患有不同严重程度阻塞性睡眠呼吸暂停综合征的成年患者的心律失常发生情况进行了分析，采用Alice 3（Healthdyne）综合多导睡眠监测仪。睡眠第一、第二和第三阶段出现的呼吸暂停发作次数实际上相同，尽管其持续时间在夜间延长，平均达到25秒（p < 0.02）。与非快速眼动睡眠相比，快速眼动睡眠期间阻塞性睡眠呼吸暂停发作导致氧合血红蛋白饱和度降低至更低值（76.1%对81.7%，p < 0.05）。心律失常在阻塞性睡眠呼吸暂停发作期间及发作后立即出现的频率高于发作前，表明它们之间存在因果关系。
