Sowerby S J, Mörth C M, Holm N G
Department of Geology and Geochemistry, Stockholm University, Stockholm, Sweden.
Astrobiology. 2001 Winter;1(4):481-7. doi: 10.1089/153110701753593883.
Equilibrium adsorption isotherms for the purine base adenine on the surface of graphite crystals have been obtained at 30, 40, 50, and 60 degrees C by frontal analysis using water as a mobile phase. These data were fitted to the Langmuir isotherm model and interpreted in terms of the well-characterized adsorbate monolayer structure. A van't Hoff plot was used to estimate the adsorption enthalpy, -delta H degree which we determined to be 20 kJ mol-1. The susceptibility of nucleic acid bases to aqueous-phase hydrolysis may have been a limiting feature for their inclusion in the primordial genetic architecture; our results suggest that the effects of temperature and the presence of inorganic solids must also be included when assessing the prebiotic availability of adenine.
通过以水为流动相的迎头分析，在30、40、50和60摄氏度下获得了嘌呤碱腺嘌呤在石墨晶体表面的平衡吸附等温线。这些数据被拟合到朗缪尔等温线模型，并根据特征明确的吸附质单层结构进行了解释。利用范特霍夫图估算了吸附焓，即 -ΔH°，我们确定其为20 kJ mol⁻¹。核酸碱基对水相水解的敏感性可能是其纳入原始遗传结构的一个限制因素；我们的结果表明，在评估腺嘌呤的益生元可用性时，还必须考虑温度和无机固体存在的影响。
