基于线粒体DNA多态性的东西伯利亚南部民族群体的分子遗传分化

[Molecular genetic differentiation of ethnic populations in Southern and Eastern Siberia based on mitochondrial DNA polymorphism].

作者信息

Derenko M V, Maliarchuk B A, Denisova G A, Dambueva I K, Kakpakov V T, Dorzhu Ch M, Luzina F A, Lotosh E A, Ondar U N, Kaplina M I, Zakharov I A

机构信息

Institute of Biological Problems of the North, Russian Academy of Sciences, Magadan, 685000 Russia.

出版信息

Genetika. 2002 Oct;38(10):1409-16.

PMID:12449652

Abstract

Using the data on mitochondrial DNA (mtDNA) polymorphism, genetic structures of the ethnic groups inhabiting South and East Siberia, including Altaians, Buryats, Tuvinians, Todjins, Tofalars, Yakuts, and Evenks were described. Mitochondrial gene pools of the populations examined were characterized by different ratios between Mongoloid (M*, C, D, E/G, G, A, B, and F) and Caucasoid (H, HV, I, J, K, T, U, and X) mtDNA lineages. All the populations studied carried a marked Mongoloid component, maximum frequency of which was observed in Evenks (92.4%) and Buryats (90.1%). Maximum frequencies of Caucasoid mtDNA lineages were detected in Tofalars (20.7%) and Yakuts (14.5%). Statistically significant interpopulation differences regarding the frequencies of mtDNA haplogroups were observed between all populations examined, excluding the pairs of Evenks-Yakuts, Evenks-Tuvinians, and Tuvinians-Todjins. Differentiation of the ethnic groups inhabiting South and East Siberia, as well as Central and Middle Asia, is discussed based on genetic, linguistic, and anthropological data.

摘要

利用线粒体DNA（mtDNA）多态性数据，描述了居住在南西伯利亚和东西伯利亚的民族的遗传结构，包括阿尔泰人、布里亚特人、图瓦人、托金人、托法拉尔人、雅库特人和埃文克人。所研究人群的线粒体基因库的特点是蒙古人种（M*、C、D、E/G、G、A、B和F）和高加索人种（H、HV、I、J、K、T、U和X）mtDNA谱系之间的比例不同。所有研究的人群都有明显的蒙古人种成分，其中埃文克人（92.4%）和布里亚特人（90.1%）的比例最高。在托法拉尔人（20.7%）和雅库特人（14.5%）中检测到高加索人种mtDNA谱系的最高频率。在所研究的所有群体之间，除了埃文克人-雅库特人、埃文克人-图瓦人以及图瓦人-托金人这几对群体外，观察到mtDNA单倍群频率存在统计学上显著的群体间差异。基于遗传、语言和人类学数据，讨论了居住在南西伯利亚和东西伯利亚以及中亚和中东地区的民族的分化情况。