Kurgaliuk N N
Ivan Franko Lviv National University, Lviv, Ukraine.
Usp Fiziol Nauk. 2002 Oct-Dec;33(4):65-79.
Recent data concerning intracellular aspects of nitric oxide at hypoxia conditions and correction means pathologic states by it. On the basis of data obtained publications and own investigations about nitric oxide influence on mitochondrial respiration and oxidative phosphorylation possible mechanism its action is discussed. We conclude that breach of macroergs output at hypoxia connect with active oxygen forms, antioxidant enzymes activity and individual peculiarities physiologic reactivity of organism.
近期有关缺氧条件下一氧化氮细胞内情况以及通过一氧化氮纠正病理状态的数据。基于已发表文献及自身研究中关于一氧化氮对线粒体呼吸和氧化磷酸化影响的数据，探讨了其可能的作用机制。我们得出结论，缺氧时高能磷酸化合物输出的破坏与活性氧形式、抗氧化酶活性以及机体生理反应性的个体特性有关。
