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[经颅磁刺激在健康受试者动态监测运动皮层状况中的应用]

[Application of transcranial magnetic stimulation for monitoring of the motor cortex condition in dynamics in healthy subjects].

作者信息

Gimranov R F

机构信息

Burdenko Neurosurgery Institute, Russian Academy of Medical Sciences, Moscow.

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2002 Sep-Oct;52(5):575-8.

PMID:12449835
Abstract

Transcranial magnetic stimulation (TMS) is used already for sixteen years for studying human central nervous system. The main objective of this work was to study motor thresholds and their hemispheric asymmetry in healthy subjects during TMS. We examined 31 righthanded healthy students. Their motor thresholds were measured in May (before vacations), September (immediately after vacations), and November (two months after vacations). Magnetic stimulator Neurosoft-MS (Ivanovo, Russia) was used for TNS of the motor cortex. It was shown that in the absence of regular active functional loads on the right hand, the motor thresholds in healthy righthanders significantly increased under the TMS of the left hemisphere, and hemispheric asymmetry disappeared under conditions both of muscle relaxation and voluntary contraction. Motor thresholds under the left-side TMS decreased and hemispheric asymmetry recovered with the restart of the regular active functional loads on the right hand.

摘要

经颅磁刺激(TMS)用于研究人类中枢神经系统已有16年。这项工作的主要目的是研究健康受试者在经颅磁刺激期间的运动阈值及其半球不对称性。我们检查了31名右利手健康学生。在五月(假期前)、九月(假期后立即)和十一月(假期后两个月)测量了他们的运动阈值。使用Neurosoft-MS磁刺激器(俄罗斯伊万诺沃)对运动皮层进行经颅磁刺激。结果表明,在右手没有定期进行主动功能负荷的情况下,健康右利手在左半球经颅磁刺激下运动阈值显著增加,并且在肌肉放松和自主收缩条件下半球不对称性消失。随着右手重新开始定期进行主动功能负荷,左侧经颅磁刺激下的运动阈值降低,半球不对称性恢复。

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