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一只恒河猴(猕猴)发生的自发性子宫肉瘤。

A spontaneous uterine sarcoma in a rhesus monkey (Macaca mulatta).

作者信息

Plesker R, Coulibaly C, Hetzel U

机构信息

Paul-Ehrlich-lnstitut, Langen, Germany.

出版信息

J Vet Med A Physiol Pathol Clin Med. 2002 Oct;49(8):428-9. doi: 10.1046/j.1439-0442.2002.00473.x.

Abstract

In primates, little has been reported about malignant mesenchymal uterine tumours. A case of a spontaneous metastasising uterine sarcoma in a 17-year-old rhesus monkey is presented. Clinically, transient abdominal pain, spasms, nausea, anaemia, a firm uterus and bloody vaginal discharge were noted. In a diagnostic laparoscopy, both massive adhesions in the lesser pelvis and 10 ml of ascites fluid were detected. In necropsy, in addition to peritonitis with massive adhesions, a cauliflower-shaped, irregular, tough, greyish-white uterine tumour was seen. Two cherry-sized tumour metastases were noticed in the greater omentum. In histology, both in the uterus and the metastases, a sarcoma with a low amount of connective tissue and well-differentiated cell nuclei was identified.

摘要

在灵长类动物中,关于子宫恶性间叶肿瘤的报道很少。本文报告了一例17岁恒河猴自发性转移性子宫肉瘤的病例。临床上,观察到短暂性腹痛、痉挛、恶心、贫血、子宫坚硬及阴道血性分泌物。在诊断性腹腔镜检查中,发现小骨盆内有大量粘连以及10毫升腹水。尸检时,除了伴有大量粘连的腹膜炎外,还可见一个菜花状、不规则、质地坚韧、灰白色的子宫肿瘤。在大网膜中发现了两个樱桃大小的肿瘤转移灶。组织学检查显示,子宫及转移灶内均为结缔组织含量低且细胞核分化良好的肉瘤。

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