Uterine angioleiomyoma in an African green monkey (Chlorocebus aethiops sabaeus).
作者信息
Valentine Matthew John, Beierschmitt Amy, DeLay Josepha, Callanan John Joseph
机构信息
Ross University School of Veterinary Medicine, Basseterre, Saint Kitts and Nevis.
Behavioural Science Foundation, Caribbean Primate Laboratory, Saint Kitts and Nevis.
出版信息
J Med Primatol. 2017 Feb;46(1):9-12. doi: 10.1111/jmp.12248. Epub 2016 Nov 8.
BACKGROUND
A uterine neoplasm was observed, as an incidental finding, during post-mortem examination of a 26-year-old female multiparous African green monkey (Chlorocebus aethiops sabaeus). The intramural, expansile, 2 to 3 cm well-demarcated, dark-red, nodular neoplasm was located on the anterior uterine body (corpus) wall.
METHODS
The mass was examined by light microscopy and by immunohistochemistry.
RESULTS
The mass was confirmed as a cavernous uterine angioleiomyoma (syn. vascular leiomyoma) characterized by abundant intratumoural vasculature lined by Factor VIII-positive endothelial cells and surrounded by smooth muscle actin-positive cell proliferations.
CONCLUSION
Angioleiomyoma sharing the characteristics of intramural human cavernous uterine angioleiomyoma should be considered in the differential diagnosis of uterine tumours in non-human primates.
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