Perez Jorge, Tardito Daniela
Istituto Scientifico H. San Raffaele, Department of Neuropsychiatry, School of Medicine, Università Vita-Salute, Via Stamira d'Ancona, Milan, Italy.
Clin Exp Hypertens. 2002 Oct-Nov;24(7-8):639-46. doi: 10.1081/ceh-120015340.
Medical complications after stroke are an important problem not only for patients, but also for their families and the clinicians who take care of them, thus representing a major public health problem. Among medical illnessess complicating stroke, in the last several years much efforts has been directed to determine the role of affective disorders. Although depression coexisting with stroke has been shown to increase levels of functional disability and reduce the effectiveness of rehabilitation, we still have much to learn about the clinical interface between such disorders. This review focuses on the data concerning the potential relationship between depression and cerebrovascular disease (CVD) and the emerging insights which may be relevant to provide directions for the development of novel research strategies on the pathogenesis and treatment of post-stroke depression.
中风后的医学并发症不仅对患者，而且对其家人以及照顾他们的临床医生来说都是一个重要问题，因此这是一个重大的公共卫生问题。在使中风复杂化的医学疾病中，过去几年人们付出了很多努力来确定情感障碍的作用。尽管已表明与中风共存的抑郁症会增加功能残疾水平并降低康复效果，但我们对这些疾病之间的临床关联仍有很多需要了解的地方。这篇综述聚焦于有关抑郁症与脑血管疾病（CVD）之间潜在关系的数据，以及可能为中风后抑郁症的发病机制和治疗方面新研究策略的发展提供指导方向的新见解。
