从湖北贝母鳞茎中分离得到的两个新的二萜二聚体，湖北贝母苷D和E。

Two new diterpenoid dimers, fritillebinide D and E, from bulbs of Fritillaria ebeiensis.

作者信息

Ruan Han-Li, Zhang Yong-Hui, Wu Ji-Zhou, Sun Han-Dong, Fujita Tetsuro

机构信息

Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China.

出版信息

J Asian Nat Prod Res. 2002 Dec;4(4):309-14. doi: 10.1080/1028602021000049113.

DOI:10.1080/1028602021000049113

PMID:12450260

Abstract

Two new ent-kaurane diterpenoid dimers, fritillebinide D (1) and fritillebinide E (2), were isolated from bulbs of Fritillaria ebeiensis G.D. Yu et G.Q. Ji. Their structures have been determined to be ent-3beta-acetoxy-kauran-16beta, 17-acetal ent-3beta-acetoxy-16beta-kauran-17(R)-aldehyde (1) and ent-3beta-acetoxy-kauran-16beta,17-acetal ent-3beta-acetoxy-16beta-kauran-17(S)-aldehyde (2) by means of spectral analysis.

摘要

从湖北贝母的鳞茎中分离得到两个新的对映-贝壳杉烷二萜二聚体，浙贝母苷D（1）和浙贝母苷E（2）。通过光谱分析确定它们的结构分别为对映-3β-乙酰氧基-贝壳杉烷-16β,17-缩醛对映-3β-乙酰氧基-16β-贝壳杉烷-17（R）-醛（1）和对映-3β-乙酰氧基-贝壳杉烷-16β,17-缩醛对映-3β-乙酰氧基-16β-贝壳杉烷-17（S）-醛（2）。