4-羟基环己烷-1-羧酸：一种从疑似代谢紊乱儿童尿液中分离出的不寻常化合物。
4-hydroxycyclohexane-1-carboxylic acid: an unusual compound isolated from the urine of children with suspected disorders of metabolism.
作者信息
Bindel T H, Fennessey P V, Miles B S, Goodman S I
出版信息
Clin Chim Acta. 1976 Jan 16;66(2):209-17. doi: 10.1016/0009-8981(76)90058-9.
PMID:1245069
Abstract
- An unknown compound has been isolated in the acidic fraction of urine samples taken from several children suspected of having metabolic disorders. 2. This unknown has been characterized using a gas chromatograph/mass spectrometer/computer system. Both the high and low resolution mass spectra have been determined and a structure proposed. 3. Authentic samples were synthesized and compared to the unknown and a final proof of structure is presented. The compound, 4-hydroxycyclohexane-1-carboxylic acid, is suspected to come from a dietary source but the actual genesis will be determined in future work.
摘要
- 从几名疑似患有代谢紊乱的儿童尿液样本的酸性部分中分离出一种未知化合物。2. 已使用气相色谱仪/质谱仪/计算机系统对该未知物进行了表征。已测定了高分辨率和低分辨率质谱，并提出了一种结构。3. 合成了标准样品并与未知物进行比较，给出了结构的最终证明。该化合物4-羟基环己烷-1-羧酸被怀疑来自饮食来源，但实际来源将在未来的研究中确定。
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