Kendrick Malcolm
Med Hypotheses. 2003 Jan;60(1):6-11. doi: 10.1016/s0306-9877(02)00319-5.
Insulin resistance would appear to be a causal factor for the development of early occlusive atherosclerosis. This paper proposes that post-prandial insulin resistance, in association with raised levels of cortisol and catecholamines, plays the major role, and may even be the primary causative factor. Therefore, factors that lead to insulin resistance in the post-prandial period, specifically stress, will accelerate the development of CHD. This may explain the low rate of CHD in France, as their eating habits (in common with many other Mediterranean countries) are more relaxed than those in Northern Europe.
胰岛素抵抗似乎是早期闭塞性动脉粥样硬化发展的一个致病因素。本文提出，餐后胰岛素抵抗与皮质醇和儿茶酚胺水平升高相关，起着主要作用，甚至可能是主要致病因素。因此，导致餐后胰岛素抵抗的因素，特别是压力，会加速冠心病的发展。这或许可以解释法国冠心病发病率较低的原因，因为他们的饮食习惯（与许多其他地中海国家一样）比北欧更为宽松。
