5-羟基分支霉素，一种由热带茎点霉产生的新天然产物，热带茎点霉是一种从螺旋藻中分离出的海洋来源真菌。
5-hydroxyramulosin, a new natural product produced by Phoma tropica, a marine-derived fungus isolated from the alga Fucus spiralis.
作者信息
Osterhage Claudia, König Gabriele M, Jones Peter G, Wright Anthony D
出版信息
Planta Med. 2002 Nov;68(11):1052-4. doi: 10.1055/s-2002-35670.
PMID:12451504
Abstract
The fungus Phoma tropica was isolated from the inner tissue of the marine brown alga Fucus spiralis. After large-scale cultivation the fungus was investigated for its secondary metabolite content and found to contain the new natural product 5-hydroxyramulosin ( 1) together with 7-methoxycoumarin. Both structures were elucidated using spectroscopic methods, mainly 1D and 2D NMR, and in the case of 1, a single crystal X-ray diffraction analysis.
摘要
热带茎点霉真菌是从海洋褐藻旋链岩藻的内部组织中分离出来的。经过大规模培养后，对该真菌的次生代谢产物含量进行了研究，发现其含有新的天然产物5-羟基分支曲菌素（1）以及7-甲氧基香豆素。两种化合物的结构均通过光谱方法进行了阐明，主要是一维和二维核磁共振，对于化合物1，还进行了单晶X射线衍射分析。
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