Bode J C, Bungartz G, Dölle W
Dtsch Med Wochenschr. 1976 Jan 9;101(2):43-7. doi: 10.1055/s-0028-1104031.
Until 1962 all patients with acute viral hepatitis admitted to the Medical University Clinic at Marburg were treated with laevulose infusions. This treatment was discontinued in 1963. Follow-up examination of 109 patients with acute hepatitis who had been given laevulose infusions and 91 who had not (both groups being similar as to age and sex and average severity of the disease) revealed that there was no significant difference between the two groups with regard to the fall in transaminase levels during the first seven weeks after the onset of jaundice. Serum-bilirubin concentration was also similar. On the other hand, the abrupt fall in serum-bilirubin concentration in the second to third week of illness, so typical of the spontaneous course, occurred a week later in those who had been given laevulose infusions. Duration of the disease until normalization of transaminase and serum-bilirubin concentration was not favourably influenced by laevulose infusions. It is concluded that such infusions do not have a favourable effect on the course of acute viral hepatitis.
直到1962年，所有住进马尔堡医科大学诊所的急性病毒性肝炎患者都接受果糖输液治疗。这种治疗方法于1963年停止。对109例接受过果糖输液治疗的急性肝炎患者和91例未接受过果糖输液治疗的患者（两组在年龄、性别和疾病平均严重程度方面相似）进行的随访检查显示，在黄疸出现后的前七周内，两组转氨酶水平下降情况没有显著差异。血清胆红素浓度也相似。另一方面，在疾病自然病程中典型的病程第二至三周血清胆红素浓度的突然下降，在接受果糖输液治疗的患者中一周后才出现。直到转氨酶和血清胆红素浓度恢复正常，疾病的持续时间并未受到果糖输液的有利影响。得出的结论是，这种输液对急性病毒性肝炎的病程没有有利影响。
