Namiki Hiroshi, Shinohara Yukito, Yamamoto Masahiro, Yonekura Yasue
Department of Educational Psychology, School of Education, Waseda University.
Seishin Shinkeigaku Zasshi. 2002;104(8):690-709.
The purpose of the present study was to develop a new neuro-psychological test for evaluating the severity of dementia based on the newly-developed theory of working memory. In Study I, twelve candidate test items, including experimental tasks used in our previous developmental studies and test items newly developed for this study, were administered to twenty four demented patients. In Study II, the same twelve test items as used in Study I were administered to eighteen normative-aged volunteers to identify the baseline of difficulty of each test item. The normative-aged group, in marked contrast to the demented group, responded correctly to nearly all of these items. These items, therefore, proved to have a discriminating power between dementia patients and normative-aged. After examining thoroughly the result of factor analysis of test scores, the difficulty of the items, and the feasibility and communicability of instructions for each item, the authors finally chose five items to construct the test. Four of these five items were ones originally developed by ourselves. In Study III, the final version of the test composed of the above five items was administered to one hundred demented patients of various etiologies. The test scores were analyzed according to the method of principal factor analysis and the theory of working memory. The results of factor analysis showed the factor pattern of a typical homogeneous test that measures a single dimension of working memory capacity. The authors, therefore, decided to apply to the test scores an item-response theory that postulates test homogeneity as a prerequisite. Based on this theory, parameters of discrimination and difficulty of each item were estimated. In addition, the scale value of each examinee, i.e. working memory capacity, was estimated from his or her response pattern to the items. When the administration of the whole test is difficult in a clinical setting, this theory makes it possible to estimate the scale value of an examinee from even a single item, though inevitably with lower reliability. Owing to the adaptability of this test, its practical utility as a measurement tool was much improved. Further, the test items and their subitems were analyzed in terms of the theory of working memory. The resulting high agreement between item difficulty and working memory demand confirmed the validity of the theoretical analysis. In addition, the result of discriminant analysis with thirty-one subitem scores of five items showed that the test discriminated correctly 79.3% of DAT and VD.
本研究的目的是基于新发展的工作记忆理论,开发一种用于评估痴呆严重程度的新型神经心理学测试。在研究I中,对24名痴呆患者进行了12个候选测试项目,包括我们之前发展研究中使用的实验任务以及为本研究新开发的测试项目。在研究II中,对18名正常年龄的志愿者进行了与研究I中相同的12个测试项目,以确定每个测试项目的难度基线。与痴呆组形成鲜明对比的是,正常年龄组对几乎所有这些项目都回答正确。因此,这些项目被证明在痴呆患者和正常年龄者之间具有区分能力。在全面检查测试分数的因素分析结果、项目难度以及每个项目指导语的可行性和可理解性之后,作者最终选择了5个项目来构建该测试。这5个项目中的4个是我们自己最初开发的。在研究III中,由上述5个项目组成的测试最终版本被施用于100名病因各异的痴呆患者。根据主因素分析方法和工作记忆理论对测试分数进行了分析。因素分析结果显示出一个典型的同质测试的因素模式,该测试测量工作记忆容量的单一维度。因此,作者决定将一种以测试同质性为前提的项目反应理论应用于测试分数。基于该理论,估计了每个项目的区分度和难度参数。此外,根据考生对项目的反应模式估计了每个考生的量表值,即工作记忆容量。当在临床环境中进行整个测试存在困难时,该理论使得即使从单个项目也有可能估计考生的量表值,尽管可靠性不可避免地较低。由于该测试的适应性,其作为测量工具的实际效用得到了很大提高。此外,根据工作记忆理论对测试项目及其子项目进行了分析。项目难度与工作记忆需求之间的高度一致性证实了理论分析的有效性。此外,对5个项目的31个子项目分数进行判别分析的结果表明,该测试正确区分了79.3%的阿尔茨海默病性痴呆和血管性痴呆。