[二次探查手术时上皮性卵巢癌患者淋巴结切除术的意义]
[Significance of lymphadenectomy in patients with epithelial ovarian cancer at second exploratory operation].
作者信息
Wang Jian-dong, Zhang Wen-hua, Wu Ling-ying, Liu Li-ying, Zhang Rong, Li Hong-jun
机构信息
Department of Gynecologic Oncology, Cancer Hospital, Peking Union Medical College, Beijing 100021, P. R. China.
出版信息
Ai Zheng. 2002 Mar;21(3):289-91.
BACKGROUND & OBJECTIVE: Lymphadenectomy in pelvic and para-aortic is one of the contents of FIGO staging operation in ovary cancer. The significance of lymphadenectomy in patients with epithelial ovarian cancer at second exploratory operation is unclear. This study was designed to assess the significance of lymphadenectomy in the patients with epithelial ovarian cancer at second exploratory operation.
METHODS
Fifteen patients with stage III and IV epithelial ovarian cancer were treated in the Cancer Hospital of Peking Union Medical College between July 1994 and October 1996 were analyzed retrospectively.
RESULTS
The degrees of differentiation were as follows: high degree in 2 patients, moderate in 7, low in 6, of the 15 patients, none of them performed lymphadenectomy and none of them was lymph node positive at second look operation. Four of 10 patients with negative findings at second look operation were recurrent, but there were no positive findings in pelvic and para-aortic lymph node.
CONCLUSIONS
Lymphadenectomy at second look operation in patients with negative lymph node at primary surgery is unnecessary.
背景与目的
盆腔及腹主动脉旁淋巴结切除术是卵巢癌国际妇产科联盟（FIGO）分期手术的内容之一。二次探查手术时对上皮性卵巢癌患者行淋巴结切除术的意义尚不清楚。本研究旨在评估二次探查手术时对上皮性卵巢癌患者行淋巴结切除术的意义。
方法
回顾性分析1994年7月至1996年10月在北京协和医院肿瘤医院接受治疗的15例Ⅲ期和Ⅳ期上皮性卵巢癌患者。
结果
15例患者的分化程度如下：高分化2例，中分化7例，低分化6例。所有患者均未行淋巴结切除术，二次探查手术时均未发现淋巴结转移阳性。二次探查手术结果阴性的10例患者中有4例复发，但盆腔及腹主动脉旁淋巴结均未发现转移阳性。
结论
初次手术时淋巴结阴性的患者二次探查手术时无需行淋巴结切除术。
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