Hu W H C, Wong W-M, Lam C L K, Lam K F, Hui W M, Lai K C, Xia H X H, Lam S K, Wong B C Y
Department of Medicine, University of Hong Kong, China.
Aliment Pharmacol Ther. 2002 Dec;16(12):2081-8. doi: 10.1046/j.1365-2036.2002.01377.x.
To study the prevalence of dyspepsia and irritable bowel syndrome and the effects of co-existing anxiety and depression on health care utilization by a population survey in Chinese.
Ethnic Chinese households were invited to participate in a telephone survey using a validated bowel symptom questionnaire and the hospital anxiety and depression scale. Gastrointestinal symptoms were classified as dyspepsia and irritable bowel syndrome according to the Rome I criteria and gastro-oesophageal reflux disease by the presence of weekly heartburn or acid regurgitation. The anxiety and depression scores were compared between patients who sought medical attention and those who did not, using multiple logistic regression analysis.
One thousand, six hundred and forty-nine subjects completed the interview (response rate, 62%). The population prevalences of dyspepsia, irritable bowel syndrome and gastro-oesophageal reflux disease were 18.4%, 4.1% and 4.8%, respectively. Dyspepsia and irritable bowel syndrome were associated with anxiety, depression, medical consultation, sick leave and adverse effects on social life. The degree of anxiety was an independent factor associated with health care-seeking behaviour in both dyspeptics (P = 0.003) and irritable bowel syndrome patients (P = 0.036).
Irritable bowel syndrome and dyspepsia are associated with anxiety, depression, significant social morbidity, health care utilization and days off work. Anxiety is an independent factor in determining health care utilization in patients with dyspepsia and irritable bowel syndrome.
通过一项中国人群调查研究消化不良和肠易激综合征的患病率以及并存的焦虑和抑郁对医疗保健利用的影响。
邀请华裔家庭参与一项电话调查,使用经过验证的肠道症状问卷和医院焦虑抑郁量表。根据罗马I标准将胃肠道症状分为消化不良和肠易激综合征,根据每周出现烧心或反酸情况诊断胃食管反流病。使用多因素逻辑回归分析比较寻求医疗关注的患者和未寻求医疗关注的患者的焦虑和抑郁评分。
1649名受试者完成了访谈(应答率62%)。消化不良、肠易激综合征和胃食管反流病的人群患病率分别为18.4%、4.1%和4.8%。消化不良和肠易激综合征与焦虑、抑郁、就医、病假以及对社会生活的不良影响相关。焦虑程度是消化不良患者(P = 0.003)和肠易激综合征患者(P = 0.036)中与寻求医疗行为相关的独立因素。
肠易激综合征和消化不良与焦虑、抑郁、显著的社会发病率、医疗保健利用和误工天数相关。焦虑是决定消化不良和肠易激综合征患者医疗保健利用的独立因素。