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卵圆孔未闭:冠状动脉搭桥术后严重发病的一个原因。

Patent foramen ovale: a cause of significant post-coronary artery bypass grafting morbidity.

作者信息

Schoevaerdts D, González M, Evrard P, Buche M, Installé E

机构信息

Departments of Intensive Care, Cardiology and Cardiovascular and Thoracic Surgery, University Clinics of Mont-Godinne, Université Catholique de Louvain, B-5530, Yvoir, Belgium.

出版信息

Cardiovasc Surg. 2002 Dec;10(6):615-7. doi: 10.1016/s0967-2109(02)00082-0.

Abstract

We describe two patients who underwent coronary artery bypass grafting complicated by postoperative hypoxemia due to a patent foramen ovale with right-to-left shunting. We discuss different hypotheses to explain the shunt: decreased right ventricular compliance, right atrial geometric changes due to septal distension or ischemia, exceeding filling pressure and localised haemorragic pericardial tamponade and low atrial pressure when correcting aortic stenosis. We emphasize the close interplay of pericardectomy and the four cardiac chambers including the distortion of the heart axis. The contrast echo produced by microbubbles of air is the safest and the most accurate procedure to detect the shunt. The two patients progressed positively with an extracorporeal circulation of short duration and without complications linked to the intervention. We conclude that postoperative unexplained hypoxemia must always exclude diagnosis of right-to-left shunting due to a patent foramen ovale (PFO).

摘要

我们描述了两名接受冠状动脉搭桥手术的患者,术后因卵圆孔未闭伴右向左分流而出现低氧血症。我们讨论了不同的假说来解释分流:右心室顺应性降低、由于间隔扩张或缺血导致的右心房几何形状改变、超过充盈压以及在纠正主动脉狭窄时局部出血性心包填塞和低心房压。我们强调心包切除术与四个心腔之间的密切相互作用,包括心脏轴的扭曲。由空气微泡产生的对比超声心动图是检测分流最安全、最准确的方法。这两名患者在短时间体外循环下病情进展良好,且未出现与干预相关的并发症。我们得出结论,术后不明原因的低氧血症必须始终排除因卵圆孔未闭(PFO)导致的右向左分流的诊断。

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