Lopez-Otsoa F, Gallego L, Towner K J, Tysall L, Woodford N, Livermore D M
Departamento de Immunologia, Microbiologia y Parasitologia, Facultad de Medicina y Odontologia, Universidad del Pais Vasco, 48080 Bilbao, Spain.
J Clin Microbiol. 2002 Dec;40(12):4741-3. doi: 10.1128/JCM.40.12.4741-4743.2002.
Eighty-two carbapenem-resistant isolates of Acinetobacter baumannii from a single hospital in Bilbao were typed into two major clusters and several subclusters. Disk synergy tests and PCR indicated the production of a zinc-independent OXA-class carbapenemase. Sequencing identified this enzyme, OXA-40, as a variant of the OXA-24-OXA-25-OXA-26 cluster.
从毕尔巴鄂一家医院分离出的82株耐碳青霉烯鲍曼不动杆菌被分为两个主要簇群和几个亚簇群。纸片协同试验和聚合酶链反应表明产生了一种不依赖锌的OXA类碳青霉烯酶。测序鉴定该酶OXA-40为OXA-24 - OXA-25 - OXA-26簇群的一个变体。