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[宫颈环扎术在早产风险患者中的价值]

[Value of cervical cerclage in patients at risk of premature delivery].

作者信息

Perrotin F, Lansac J, Body G

机构信息

Département de Gynécologie Obstétrique, Médecine Foetale et Reproduction Humaine, Hôpital Bretonneau, CHU de Tours, 2, boulevard Tonnellé, 37044 Tours Cedex 1, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2002 Nov;31(7 Suppl):5S66-73.

PMID:12454628
Abstract

Cervical cerclage is not recognized as the usual treatment of threatened premature delivery including uterine contractions and cervical modifications. Pregnant women with a threatened premature delivery limited to the presence of a short cervix at digital examination or internal scan may however be offered therapeutic cerclage, different from prophylactic first trimester cervical cerclage, when cervical insufficiency is suspected. Studies on cervical cerclage to prevent premature delivery suffered a poor design and do not allow any strong definitive conclusion. In the presence of a shortened or dilated cervix at digital examination without uterine contractions, there is no strong scientific evidence to support the practice of therapeutic cervical cerclage. Conversely there is however no strong scientific evidence to reject this procedure especially in early pregnancy (before the end of the second trimester). Therefore therapeutic cervical cerclage remains a possible option only if premature labor, intrauterine infection or placental abruption have been ruled-out by a 48 hours inpatient bed rest. In patients without previous history of premature delivery or second trimester miscarriage, there is no scientific evidence to support therapeutic cervical cerclage in presence of a short cervix. Moreover, in this low-risk group cervical length ultrasound screening is not recommended. In patients with one or more previous premature deliveries or second trimester miscarriage but who do not reach Royal College criteria for prophylactic cervical cerclage, there is currently not enough evidence to support a policy of therapeutic cervical cerclage compared to bed rest. This latter recommendation may however depend on the severity of previous obstetrical history.

摘要

宫颈环扎术并非被公认为是治疗包括子宫收缩和宫颈改变在内的先兆早产的常规方法。然而,对于那些在指诊或经阴道超声检查时仅发现宫颈短而被诊断为先兆早产的孕妇,当怀疑有宫颈机能不全时,可考虑进行治疗性宫颈环扎术,这与孕早期预防性宫颈环扎术不同。关于宫颈环扎术预防早产的研究设计欠佳,无法得出任何强有力的确定性结论。在指诊时发现宫颈缩短或扩张但无子宫收缩的情况下,没有强有力的科学证据支持治疗性宫颈环扎术的实施。相反,也没有强有力的科学证据反对这一手术,尤其是在孕早期(妊娠中期结束前)。因此,只有在经过48小时住院卧床休息排除早产、宫内感染或胎盘早剥后,治疗性宫颈环扎术才仍然是一种可能的选择。对于既往无早产或妊娠中期流产史的患者,没有科学证据支持在宫颈短的情况下进行治疗性宫颈环扎术。此外,在这个低风险组中,不建议进行宫颈长度超声筛查。对于有一次或多次既往早产或妊娠中期流产史但未达到皇家学院预防性宫颈环扎术标准的患者,与卧床休息相比,目前没有足够的证据支持治疗性宫颈环扎术的策略。然而,后一项建议可能取决于既往产科病史的严重程度。

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1
[Value of cervical cerclage in patients at risk of premature delivery].[宫颈环扎术在早产风险患者中的价值]
J Gynecol Obstet Biol Reprod (Paris). 2002 Nov;31(7 Suppl):5S66-73.
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[What should you tell a patient with a history of cervical incompetence in the first trimester?].对于孕早期有宫颈机能不全病史的患者,你应该告知什么?
Gynecol Obstet Fertil. 2006 Feb;34(2):137-41. doi: 10.1016/j.gyobfe.2005.11.007. Epub 2006 Feb 17.
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[Second trimester cerclage of short cervixes: which technique to use? A retrospective study of 25 cases].[孕中期短宫颈环扎术:采用哪种技术?25例回顾性研究]
J Gynecol Obstet Biol Reprod (Paris). 2002 Nov;31(7):640-8.
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Cervical insufficiency and cervical cerclage.宫颈机能不全与宫颈环扎术
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Ultrasound Obstet Gynecol. 2002 May;19(5):475-7. doi: 10.1046/j.1469-0705.2002.00673.x.
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Indications for and pregnancy outcomes of cervical cerclage: 11-year comparison of patients undergoing history-indicated, ultrasound-indicated, or rescue cerclage.宫颈环扎术的指征及妊娠结局:对因病史指征、超声指征或补救性环扎术而接受手术的患者进行的11年比较。
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Prematurity prevention: the role of cerclage.早产预防:宫颈环扎术的作用。
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Final results of the Cervical Incompetence Prevention Randomized Cerclage Trial (CIPRACT): therapeutic cerclage with bed rest versus bed rest alone.宫颈机能不全预防随机宫颈环扎试验(CIPRACT)的最终结果:治疗性宫颈环扎联合卧床休息与单纯卧床休息的比较。
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Cervical cerclage in the prevention of preterm birth.宫颈环扎术预防早产
Best Pract Res Clin Obstet Gynaecol. 2007 Oct;21(5):831-42. doi: 10.1016/j.bpobgyn.2007.03.009. Epub 2007 May 10.