Branica Srećko, Sprem Nikola, Mihelić Damir, Zobundzija Mladen, Cvoriscec Dubravka, Cacić Melita, Dawidowsky Krsto
ENT Department, School of Medicine, University of Zagreb, Department of Anatomy, Histology and Embriology, School of Veterinary Medicine.
Acta Med Croatica. 2002;56(1):11-5.
The left chorda tympani nerve was interrupted through meatus acusticus externus in ten dogs. In total, 40 dog salivary glands (20 submandibular and 20 sublingual) innervated via chorda tympani were examined. Twenty glands (10 submandibular and 10 sublingual) on the left side were deprived of parasympathetic innervation by chordectomy, whereas contraleteral glands, on the right side, served as controls. Biochemical analysis showed that the interruption of chorda tympani did not cause any significant changes in the concentrations of eight enzymes investigated, i.e. lactate dehydrogenase, alkaline phosphatase, acid phosphatase, amylase, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase and creatine kinase. There were no significant changes in the concentrations of most important extracellular ions (sodium, potassium, chloride and phosphorus) in the right glands, but the loss of parasympathetic innervation in the left glands was found to cause a statistically significant decrease in the concentration of potassium as intracellular cation and of phosphorus as extracellular anion.
在10只犬中，经外耳道切断左侧鼓索神经。总共检查了40个由鼓索神经支配的犬唾液腺（20个下颌下腺和20个舌下腺）。左侧的20个腺体（10个下颌下腺和10个舌下腺）通过鼓索神经切除术失去了副交感神经支配，而右侧的对侧腺体作为对照。生化分析表明，鼓索神经切断术并未导致所研究的8种酶（即乳酸脱氢酶、碱性磷酸酶、酸性磷酸酶、淀粉酶、天冬氨酸转氨酶、丙氨酸转氨酶、γ-谷氨酰转移酶和肌酸激酶）的浓度发生任何显著变化。右侧腺体中最重要的细胞外离子（钠、钾、氯和磷）的浓度没有显著变化，但发现左侧腺体副交感神经支配的丧失导致细胞内阳离子钾和细胞外阴离子磷的浓度在统计学上显著降低。
